Lyon are slight favorites for this European Challenge Cup encounter with odds around 1.90, while Benetton Treviso are available at approximately 2.05. Lyon's home advantage at Mahmut Stadium and their competitive pool position give them the edge, though Benetton showed strong form with a 44-31 victory over Perpignan on December 13, 2025 with DexWin - Best Odds on Your Favourite Sports.

The match kicks off at 1:00 PM UTC on January 18, 2026, which corresponds to 2:00 PM CET (Central European Time) at the host venue in Istanbul.

The match will be played at Mahmut Stadium in Istanbul, Turkey, a modern rugby facility with a capacity of approximately 6,000 seats. The venue serves as Lyon's designated home ground for European Challenge Cup fixtures this season.

Lyon are predicted to secure victory with moneyline odds of 1.90 based on their home advantage and pool positioning. Benetton enter as underdogs at 2.05 odds, but their recent 44-31 win over Perpignan demonstrates attacking capability that could trouble Lyon's defense in an open contest.

Direct head-to-head records between Lyon and Benetton Treviso in the Challenge Cup are limited, as this represents a relatively new competitive pairing. Both teams are competing in Pool 2 of the 2025-26 EPRC Challenge Cup, making this fixture crucial for their progression toward the knockout stages.