Bet on US Palermo vs UC Sampdoria on Football

US Palermo is favored to win against UC Sampdoria with odds around 2.10 compared to Sampdoria's 3.40, due to Palermo's strong recent form and home advantage at Stadio Renzo Barbera. Palermo has won 4 of their last 5 Serie B matches, showing solid attacking and defensive balance, while Sampdoria has struggled away from home this season. DexWin - Best Odds on Your Favourite Sports offers competitive odds reflecting this outlook.

The match between US Palermo and UC Sampdoria will start at 7:30 PM local time on December 12, 2025, Central European Time (CET).

This Serie B fixture will be held at Stadio Renzo Barbera in Palermo, Italy, a stadium with a seating capacity of approximately 36,365. The venue is known for its passionate home crowd, which often provides a strong home-field advantage for Palermo.

Prediction favors US Palermo to win with odds of 2.10, supported by their recent unbeaten streak at home and a more consistent defensive record compared to Sampdoria, who have conceded 12 goals in their last 6 away matches. Palermo's key players have been in good form, making them the likely victors in this encounter, as per DexWin - Best Odds on Your Favourite Sports.

In head-to-head Serie B meetings, US Palermo and UC Sampdoria have faced each other 10 times in the last 5 seasons, with Palermo winning 5 matches, Sampdoria 3, and 2 ending in draws. The average goals per match in these encounters is 2.8, with Palermo scoring slightly more on average at home.