SS Lazio is favored to win against US Lecce with odds around 1.60 compared to Lecce's 5.00, reflecting Lazio's stronger home form and higher points per game this season. Lazio has won their last two home matches and maintains a 100% win rate at home recently, while Lecce struggles with only one win in eight league games this season.

The match starts at 5:00 PM UTC on November 23, 2025, which corresponds to 6:00 PM CET local time in Rome, Italy.

The game will be played at Stadio Olimpico in Rome, Italy, which is Lazio's home stadium. Stadio Olimpico has a seating capacity of approximately 70,634 and is known for hosting major Serie A matches and international fixtures.

Prediction favors Lazio to win with moneyline odds near 1.60, supported by their solid defensive record at home with 80% clean sheets overall and 100% at home. The expected scoreline is 1-0 with under 2.5 goals likely, considering both teams' recent low scoring trends and Lazio's strong defensive stats.

In their recent head-to-head encounters, Lazio holds a clear advantage with multiple wins over Lecce, including a 1-0 victory predicted for this match. Lecce's last win against Lazio was in May 2025 at Rome, but overall Lazio has dominated these fixtures with a higher win percentage and better goal difference.