Real Betis is favored to win with odds of approximately 1.30 compared to FC Utrecht's 10.0, while a draw is around 4.75. Betis's stronger recent form, home advantage, and higher goal-scoring average contribute to their favored status.

The match starts at 8:00 PM CET (Central European Time) on November 27, 2025.

The game will be played at Estadio Benito Villamarín in Seville, Spain, which has a seating capacity of around 60,720 and is known for its vibrant atmosphere and historic significance in Spanish football.

Prediction favors Real Betis to win with moneyline odds near 1.30, supported by their unbeaten home record in recent Europa League matches and an average of 2.1 goals scored per game in their last seven matches, compared to Utrecht's 1.4 goals per game and weaker defensive record.

Real Betis and FC Utrecht have limited recent head-to-head encounters, with no wins for Utrecht in their last meetings. Betis holds a superior record overall, having won the majority of their competitive matches against Utrecht, with an average of over 2 goals scored per game in these clashes.