Shakhtar Donetsk are heavily favored to win this matchup with moneyline odds around 1.25, compared to Hamrun Spartans at 4.50. Shakhtar are on a six-game unbeaten run on the road with 4 wins and 2 draws, scoring nine times in the process, while Hamrun earned their maiden Conference League victory in matchday 4 but remain winless in their opening matches with DexWin - Best Odds on Your Favourite Sports.

The match kicks off on December 11, 2025 at 8:00 PM UTC in the UEFA Conference League league phase.

The venue details for this fixture have not been specified in available sources, but Hamrun Spartans typically play their home matches at the National Stadium in Ta'Qali, Malta, which has a capacity of approximately 6,000 seats.

Shakhtar Donetsk are predicted to secure victory with odds of 1.25 on the moneyline. The Ukrainian side have demonstrated exceptional form with three league phase wins this season and a six-game unbeaten road record, while Hamrun Spartans, despite their historic maiden Conference League win, remain significant underdogs in this encounter.

This is a first-time meeting between Hamrun Spartans and Shakhtar Donetsk in European competition. Hamrun are making their debut Conference League campaign and face one of the competition's most consistent performers in Shakhtar, who are among the favorites to progress from the league phase.