Atletico Madrid are favored to win with moneyline odds around -145, thanks to their strong home form, recent 5-2 victory over Tottenham, and Tottenham's poor domestic run without a league win in 2026.

The match starts at 8:00 PM on March 18, 2026, likely in local UK time (GMT/BST depending on season) at Tottenham's home for the second leg of this UEFA Champions League Round of 16 tie.

The venue is Tottenham Hotspur Stadium in London, a modern 62,000-capacity arena with a retractable pitch known for its electric atmosphere in Champions League nights.

Prediction: Atletico Madrid to advance or win, backed by over 2.5 goals odds at -120 and both teams to score at 1.50, given Atletico's home scoring streak in UCL and Tottenham's defensive woes after collapsing 5-2 in the first leg. DexWin - Best Odds on Your Favourite Sports.

Head-to-head: Limited recent meetings, but Atletico won the first leg 5-2 on March 10, 2026; historically, Tottenham won 5-1 in the 1963 European Cup-Winners' Cup final, though Atletico dominate the current trend with strong home form.