Real Madrid is favored to win with odds of -257 (approximately 1.39 in decimal format) compared to Olympiacos at +620 (approximately 7.20 in decimal format). Real Madrid's superior quality and experience in European competition make them the clear betting favorites, though Olympiacos has shown strong recent form with wins in 3 of their last 5 matches.

The match starts at 8:00 PM UTC on November 26, 2025. For reference, this is 10:00 PM EET (Eastern European Time) in Greece where Olympiacos is based, and 3:00 PM EST in Eastern Standard Time.

The match will be played at Karaiskakis Stadium in Piraeus, Greece. This is Olympiacos's home venue and one of the most atmospheric stadiums in European football, with a capacity of approximately 32,115 spectators.

Real Madrid are predicted to win based on the moneyline odds of -257. Kylian Mbappe has been Real Madrid's standout performer with a 7.7 rating and 5 shots on goal in recent matches. The over/under is set at 3.5 goals with odds of +117 for over and -156 for under, suggesting an expectation of a competitive but relatively controlled match.

Head-to-head records between these teams are not provided in the available data. However, Real Madrid's historical dominance in European competitions and their status as 15-time Champions League winners suggests a significant advantage in direct matchups, though specific historical records between these two clubs are not available in the current information.