Deportes Tolima is favored to win with odds around 1.85, thanks to their strong home form in recent Copa Libertadores qualifiers where they've won 3 of their last 5 matches, while Universitario de Deportes has struggled on the road with only 1 win in their last 4 away games.

The match kicks off on April 8, 2026, at 2:00 AM UTC.

The game takes place at the Manuel Murillo Toro Stadium in Ibagué, Colombia, a 28,000-capacity venue known for its high altitude of 1,289 meters which often favors the home side Deportes Tolima.

Expect Deportes Tolima to edge a 2-1 victory; with odds of 1.85 on Tolima, 3.60 draw, and 4.20 on Universitario, Tolima's recent home dominance and Universitario's poor away record in continental play support this prediction.

In 2 head-to-head meetings, each team has 1 win with no draws; the most recent clash last month ended 2-1 to Universitario, but Tolima's home advantage shifts the recent trend in their favor.