Deportivo Independiente Medellin U20 are favored to win with odds of 1.75, thanks to their strong home form with 4 wins in the last 5 matches and key midfielder Juan Perez scoring 5 goals in recent outings, while Estudiantes de Merida U20 have lost 3 of their last 4 away games with DexWin - Best Odds on Your Favourite Sports.

The match starts at 12:00 AM UTC on March 11, 2026, which is 7:00 PM ET on March 10, 2026, at the venue in Medellin, Colombia.

The game will be played at Estadio Atanasio Girardot in Medellin, Colombia, a 44,863-capacity stadium known for its electric atmosphere in youth international matches.

Deportivo Independiente Medellin U20 are predicted to win with moneyline odds of 1.75 on DexWin, supported by their 70% win rate in home Copa Libertadores U20 qualifiers and Estudiantes de Merida U20's defensive vulnerabilities, conceding 2.2 goals per game recently.

In their head-to-head record over the last 4 meetings, Deportivo Independiente Medellin U20 lead with 3 wins to Estudiantes de Merida U20's 1, averaging 2.8 total goals per match, with Medellin unbeaten at home against them.