Karlsruher SC are likely to be slight favorites based on their more established recent presence in the 2. Bundesliga and stronger overall squad depth, while SC Preußen Münster come in as underdogs newly pushing at this level. Early market indications for a neutral-ground style matchup suggest Karlsruher SC in the 2.10–2.30 range and Preußen Münster around 3.00–3.30, with the draw near 3.40, reflecting higher win probability for the visitors on DexWin - Best Odds on Your Favourite Sports.

The SC Preußen Münster vs Karlsruher SC 2. Bundesliga match on 17 January 2026 is scheduled to kick off at 12:00 PM local time in Germany, which corresponds to 11:00 AM UTC in winter. Fans should verify on matchday if any slight adjustments occur due to TV scheduling.

This fixture is set to be played in Münster at SC Preußen Münster’s home ground, Stadion an der Hammer Straße, a compact football-specific venue traditionally holding around 14,000 spectators. The stadium’s intimate design and typically vocal home support can give Preußen Münster a noticeable home-field advantage against visiting 2. Bundesliga sides.

From a prediction standpoint, Karlsruher SC’s higher league stability and better recent second-tier form make them the logical pick, with value on an away win if odds remain above 2.10. However, considering Preußen Münster’s strong home backing and adjustment curve in 2. Bundesliga, combining a Karlsruher SC win with draw-no-bet or using an Asian handicap line around 0 or -0.25 can offer a more balanced risk profile.

Historically, meetings between SC Preußen Münster and Karlsruher SC have been relatively rare in recent years, with notable clashes coming when both clubs shared the same division, including a key win by Karlsruher SC that helped them secure promotion back to the 2. Bundesliga. Overall, head-to-head records slightly lean towards Karlsruher SC, but the sample size is small enough that current form and league status should be weighted more heavily than older results.