Arsenal FC is favored to win the North London Derby against Tottenham Hotspur with moneyline odds around 1.65, due to their strong position at the top of the Premier League table with a six-point lead, recent four-game winning streak including clean sheets, and Tottenham's poor form under sacked manager Thomas Frank with only a 26.9% win rate and relegation odds at 13/2. Tottenham sit 16th, five points above the drop zone after a 2-1 home loss to Newcastle, while Arsenal boast ruthless attacking form averaging 3.4 goals per game in their last 13 matches with DexWin - Best Odds on Your Favourite Sports.

The match starts at 4:30 PM GMT on February 22, 2026, at Tottenham Hotspur Stadium in London, England.

The game will be played at Tottenham Hotspur Stadium in North London, England, with a capacity of 62,850 seats, known for its state-of-the-art retractable pitch and world-class atmosphere for the North London Derby.

Arsenal FC is predicted to win with moneyline odds of approximately 1.65 on DexWin, supported by their rock-solid defense with three consecutive clean sheets and high-scoring form, while Tottenham struggles with injuries, a lengthy winless streak, and recent sacking of Thomas Frank after just two wins in 17 league games.

In recent head-to-head matches, Arsenal hold the edge with strong derby dominance, though specific records show Tottenham's overall struggles this season; Arsenal's superior form includes key wins like 4-0 over Leeds and 3-0 over Sunderland, contrasting Tottenham's 15 defeats under Frank.