Atlético Junior is favored to win the match with odds around 1.95, given their stronger recent form and home advantage considerations in the Primera A. Independiente Santa Fe enters as the underdog at approximately 1.90 odds, though they remain competitive in this Colombian league fixture.

The match starts at 2:00 PM Colombia Time (UTC-5) on February 22, 2026, which corresponds to 7:00 PM UTC. This afternoon kickoff is typical for Colombian Primera A matches and allows for optimal viewing conditions.

The match will be played at the Estadio Metropolitano de Barranquilla or the home stadium of Atlético Junior in Barranquilla, Colombia. The venue has a capacity of approximately 37,000 seats and is one of the premier football stadiums in the Colombian Caribbean region.

Atlético Junior are predicted to secure victory with moneyline odds of 1.95 on DexWin - Best Odds on Your Favourite Sports. Junior's recent performance and league standing suggest they have the edge, though Independiente Santa Fe's defensive organization could make this a closely contested encounter.

In their head-to-head record, Atlético Junior leads with 2 wins compared to Independiente Santa Fe's 1 win, with 1 draw between the teams. This historical advantage, combined with Junior's current form, positions them as slight favorites for this Primera A matchup.