Independiente Santa Fe is favored to win with odds of 1.75, thanks to their strong home form with 4 wins in the last 5 home games and key player Hugo Rodallega scoring 7 goals in the past month. Alianza Valledupar struggles away, losing 3 of their last 4 road matches, making Santa Fe the clear choice on DexWin - Best Odds on Your Favourite Sports.

The match starts at 1:30 AM UTC on March 15, 2026, which is 8:30 PM ET on March 14 or 10:30 PM COT local time in Colombia.

The game will be played at Estadio Nemesio Camacho El Campín in Bogotá, Colombia, with a capacity of 36,343 seats and known for its high-altitude advantage favoring home teams like Independiente Santa Fe.

Independiente Santa Fe is predicted to win with moneyline odds of 1.75, supported by their recent 3-1-1 form and defensive record of just 4 goals conceded in 5 games; over/under is leaning under 2.5 at 1.90 odds given both teams' low-scoring recent outings.

In the last 10 head-to-head meetings, Independiente Santa Fe leads with 6 wins to Alianza Valledupar's 2 wins and 2 draws, averaging 2.3 total goals per match; Santa Fe has won the last 3 encounters at home 2-0, 1-0, and 3-1.