Club Atletico Junior is slightly favored to win with odds around 2.10 compared to Atletico Nacional Medellin at approximately 2.50, based on recent form where Junior remains unbeaten in their last five meetings against Atletico Nacional and holds a strong away record this season.

The match starts at 9:00 PM local time (Colombia Time, COT, UTC-5) on November 12, 2025.

The game will be played at Estadio Metropolitano Roberto Meléndez in Barranquilla, Colombia, which has a capacity of about 46,000 seats and is known for its vibrant atmosphere and strong home support for Junior.

Prediction favors Club Atletico Junior to win with moneyline odds near 2.10, supported by their unbeaten streak against Atletico Nacional in recent encounters and their current strong away performance, while Atletico Nacional has scored 5 goals in their last 5 matches but struggled to secure wins against Junior.

In the last 5 head-to-head matches, Club Atletico Junior has won 3 and drawn 2 against Atletico Nacional Medellin, maintaining an unbeaten record. Historically, Junior has won 14 of the past 58 meetings, showing a competitive edge in this fixture.