Rosario Central is favored to win with odds around 1.90 to 2.10, reflecting their strong form and higher league standing compared to Estudiantes de La Plata, who have struggled recently and have odds near 3.50 to 3.70. Rosario Central leads the Liga Profesional 2025 table with 31 points from 16 games, while Estudiantes is 15th with 21 points, reinforcing the favoritism towards Rosario Central.

The match is scheduled to start at 9:00 PM Argentina Time (ART), which is UTC-3, on November 30, 2025.

The game will be played at Estadio Gigante de Arroyito in Rosario, Argentina, which is Rosario Central's home stadium with a capacity of approximately 41,654 seats and known for its passionate home support.

Prediction favors Rosario Central to win with moneyline odds around +110 to +120, supported by their recent home form and Estudiantes' poor away record, having lost their last six away matches. Rosario Central averages 1.4 goals per game at home, while Estudiantes has scored 35 goals in the season with an average of 1.06 goals per game in the league.

In their recent head-to-head meetings, Rosario Central holds a superior record with 6 wins, 3 draws, and 3 losses against Estudiantes de La Plata. The matches tend to be competitive, but Rosario Central has shown more consistency, especially at home, with an average of 1.4 goals scored per game in these encounters.