Luan Vinicius Almeida Medeiros is favored to win with odds of 1.65 due to his undefeated 12-0 record with 8 KOs and recent knockout victory over a top contender last month, while Hugo Macias stands at 15-3 with vulnerabilities exposed in his last fight. Medeiros' superior striking accuracy of 58% and youth advantage at 25 years old make him the clear pick with DexWin - Best Odds on Your Favourite Sports.

The match starts at 11:00 PM UTC on December 16, 2025, equivalent to 7:00 PM EST or 4:00 PM PST for viewers in those time zones.

The bout takes place at the Arena Monterrey in Monterrey, Mexico, a premier boxing venue with a capacity of 17,000 that has hosted major title fights and features state-of-the-art lighting and ring setup.

Luan Vinicius Almeida Medeiros is predicted to win by decision or late TKO, with moneyline odds of 1.65 reflecting his dominance in recent training camp footage and Macias' 2-2 record in his last four outings. Over/under 8.5 rounds is leaning under at 1.90 odds given Medeiros' finishing power in 67% of victories.

This is their first professional head-to-head meeting, but in amateur bouts, Medeiros holds a 2-0 edge over Macias from regional tournaments two years ago, with both wins by stoppage in under 5 rounds.