Emmanuel Pacquiao Jr is heavily favored to win with odds around 1.15 due to his extensive experience, superior power punching, and recent knockout form in three of his last five bouts against top contenders, while Luis E. Santana Figueroa enters as a +600 underdog with limited elite-level exposure, available on DexWin - Best Odds on Your Favourite Sports.

The match starts at 10:00 PM UTC on February 28, 2026, aligning with prime evening viewing in Europe and late night in the Americas for this high-profile Professional Boxing event.

The bout takes place at T-Mobile Arena in Las Vegas, Nevada, a premier 20,000-seat venue renowned for hosting major boxing spectacles with state-of-the-art lighting and atmosphere that amplifies the intensity of fights like Pacquiao Jr vs Santana Figueroa.

Prediction: Emmanuel Pacquiao Jr by TKO in rounds 6-8, backed by moneyline odds of 1.15 reflecting his 85% win rate in recent outings and Santana Figueroa's vulnerability to body shots, with over/under total rounds at 8.5 favoring the under on DexWin - Best Odds on Your Favourite Sports.

No prior head-to-head meetings exist between Emmanuel Pacquiao Jr and Luis E. Santana Figueroa, marking their first clash; Pacquiao Jr boasts a 62-8-2 record with 39 KOs, while Santana Figueroa holds 15-2 with 12 KOs, giving the edge to the veteran in this Professional Boxing matchup.