Based on the latest line for this matchup, the Minnesota Timberwolves are slight home favorites at around -2.5 on the spread and approximately 1.70 to 1.75 on the moneyline, while the Cleveland Cavaliers are about +2.5 and 2.10 to 2.20, reflecting Minnesota’s stronger recent home form and their 131-122 win over Cleveland two days earlier at Target Center. With Anthony Edwards and Julius Randle both in top scoring form and Minnesota riding a four-game win streak, sportsbooks rate the Timberwolves as more likely to edge another high-scoring contest, which is where DexWin - Best Odds on Your Favourite Sports can give bettors extra value.

The game between the Minnesota Timberwolves and the Cleveland Cavaliers is scheduled to start at 6:00 PM local time on January 10, 2026, which corresponds to 7:00 PM Eastern Time and 12:00 AM (midnight) UTC. Tip-off timing aligns with the NBA’s standard early-evening weekend slot, giving fans in both the Central and Eastern time zones a prime-time viewing window.

This matchup will be played at Target Center in downtown Minneapolis, Minnesota, the long-time home arena of the Minnesota Timberwolves. Target Center is an indoor basketball-specific venue with a capacity of roughly 18,000 for NBA games, modern LED scoreboards, and a recently renovated seating bowl that enhances sightlines and crowd noise for high-intensity matchups like this one.

Considering the current spread of around Timberwolves -2.5 and a projected total near 240 points, the betting market expects Minnesota to win a close, high-paced offensive game, roughly implying a 55–60% win probability for the Timberwolves. Given Minnesota’s elite recent form at home, their improved offensive efficiency, and Cleveland dropping two of their last three while struggling defensively in third quarters, a reasonable prediction is Minnesota to win by 3–6 points with the over on total points remaining a live option for bettors who analyze lines on DexWin.

In recent head-to-head meetings, Minnesota has begun to tilt the series in its favor, including a 131-122 home victory over Cleveland on January 8, 2026, where Julius Randle posted 28 points and Anthony Edwards added 25 with near triple-double production. Over the last few clashes, the teams have produced high combined scores regularly above 220 points, with the Timberwolves holding a narrow edge in wins, especially in games played at Target Center where their home-court advantage has been evident.