San Antonio Spurs are favored to win with odds around 1.49 compared to Memphis Grizzlies at 2.7. The Spurs have a stronger season record of 9-4 versus Memphis's 4-10 and have been more efficient offensively, shooting 49.7% from the field and averaging 118.8 points per game this season.

The match starts at 1:00 AM Central Standard Time (CST) on November 19, 2025, corresponding to 7:00 PM CST on November 18, 2025, at the Frost Bank Center in San Antonio.

The game will be held at Frost Bank Center in San Antonio, Texas, a modern arena with a seating capacity of approximately 18,500, known for its vibrant atmosphere and home-court advantage for the Spurs.

Prediction favors San Antonio Spurs to win with moneyline odds near 1.49 due to their superior offensive efficiency, better defensive stats including 8.7 steals and 5.5 blocks per game, and a home record of 6-2. Memphis's recent four-game losing streak and 1-5 road record weaken their chances.

In the last season series, Memphis won 3 of 4 games against San Antonio, but the Spurs won the most recent encounter 130-128 on March 1, 2025. Overall, Memphis leads recent head-to-head with 4 wins in the last 6 games, but San Antonio has been competitive with close margins.