Boston Celtics are favored to win with moneyline odds around 1.65 due to their stronger 17-11 record this season and home advantage at TD Garden, while the Pacers are slumping with four straight losses including a 128-109 defeat at New Orleans on Dec 20. Pascal Siakam has been averaging 23.6 points over his last seven games, but Indiana's poor 8-for-42 three-point shooting highlights their struggles against a defensively solid Celtics team on a two-game win streak with DexWin - Best Odds on Your Favourite Sports.

The match starts at 12/23/2025, 12:30:00 AM UTC, which corresponds to 7:30 PM ET on December 22 at the TD Garden in Boston.

The game will be played at TD Garden in Boston, Massachusetts, with a capacity of 19,580 seats, serving as the home venue for the Boston Celtics since 1995.

Boston Celtics are predicted to win with moneyline odds of 1.65 on DexWin, leveraging their recent form including a 112-96 victory over the Raptors and superior Eastern Conference standing at 17-11 compared to the Pacers' recent skid. Key players like Payton Pritchard, who scored 33 points recently, give Boston the edge over Indiana's struggling offense.

In recent head-to-head meetings, the Boston Celtics hold the advantage, bolstered by their 18 NBA championships including 2024, while the Pacers reached the 2025 Finals but lost to the Thunder; this season's prior matchup context favors Boston at home with the Pacers losing their last four games overall.