San Lorenzo de Almagro is favored to win with odds around 1.65 due to their stronger recent form, including an 80-75 overtime victory over Unión de Santa Fe on December 5, 2025, and superior league standing in Liga Nacional. Unión de Santa Fe struggles away, winning only 2 of their last 5 road games, making San Lorenzo the clear pick with DexWin - Best Odds on Your Favourite Sports.

The match starts at 11:30 PM UTC on January 19, 2026, at the Estadio Ángel P. Núñez in Santa Fe, Argentina.

The game is at Estadio Ángel P. Núñez, home of Unión de Santa Fe, with a capacity of approximately 1,200 spectators, known for its intimate atmosphere in Liga Nacional matches.

San Lorenzo de Almagro is predicted to win with moneyline odds of 1.65 on DexWin, backed by their 4-1 record in the last 5 head-to-heads and key player Marcos Mata averaging 18 points recently. Over/under is set at 162.5, leaning under based on their defensive average of 78 points allowed in recent games.

In head-to-head matchups, San Lorenzo leads with 6 wins to Unión de Santa Fe's 3 in the last 10 meetings, averaging 82 total points per game. Their most recent clash on December 5, 2025, ended 80-75 in overtime favoring San Lorenzo.