Seattle Mariners are favored to win this MLB Spring Training matchup due to their stronger projected season performance with 90.1 win average and 73.7% playoff odds, compared to the Padres' declining projections of 83.3 wins and 40.9% playoff odds after losing key players like Dylan Cease; current betting odds list Mariners at 1.85 and Padres at 2.10 with DexWin - Best Odds on Your Favourite Sports.

The match starts at 8:10 PM PST on February 28, 2026, at the Peoria Sports Complex in Peoria, Arizona, a key spring training hub for Cactus League games.

The game is at Peoria Sports Complex in Peoria, Arizona, with a capacity of 11,333 seats and modern facilities shared by the Mariners and Padres, featuring excellent sightlines and player development amenities.

Prediction favors a Seattle Mariners victory with moneyline odds of 1.85 on DexWin, supported by their elite projected rotation and recent spring form showing a 7-4 win over the Padres earlier this month, while San Diego's bullpen reliance poses risks in a short training contest.

In head-to-head matchups, Seattle Mariners hold a 7-4 edge from their February 20, 2026 Spring Training game; historically in recent regular seasons, the teams split evenly with 5 wins each over the last 10 meetings, averaging 8.2 total runs per game.