The Los Angeles Angels are slight favorites in this Spring Training matchup against the San Diego Padres, with the Angels projected to have a stronger 2026 season based on recent roster improvements and health recoveries. The Padres are dealing with significant offensive questions after losing key players like Dylan Cease and Luis Arraez in the offseason, while the Angels look to build momentum with players like Jo Adell coming off a 37-home run season.

The match starts at 8:10 PM PST on February 25, 2026, during the opening day of Spring Training games across MLB.

The game will be played at Tempe Diablo Stadium in Tempe, Arizona, which serves as the spring training home for the Los Angeles Angels and hosts various MLB Spring Training matchups throughout the preseason.

The Los Angeles Angels are favored to win this Spring Training contest as they enter 2026 with better projected performance metrics and roster stability compared to the Padres, who are projected to drop from 90 wins last season to just 79 wins in 2026. The Angels' pitching staff, led by José Soriano making his Cactus League debut, appears more reliable than the Padres' rotation questions at the fifth starter position.

Spring Training records between these teams are not typically tracked as head-to-head statistics in the same manner as regular season games, but both clubs will be using this early matchup to evaluate roster depth and player performance before the regular season begins on March 27, 2026.