Houston Astros are favored to win this MLB Spring Training matchup against the Miami Marlins due to their superior projected season performance with 84.9 win average and stronger playoff odds of around 35-48%, compared to Marlins' 71.8 wins and just 5.7% playoff chances; early odds list Astros at 1.65 with Marlins at 2.35 on DexWin - Best Odds on Your Favourite Sports.

The match starts at 6:10 PM ET on February 25, 2026, at the Astros' Spring Training facility in West Palm Beach, Florida.

The game is at CACTI Park of The Palm Beaches in West Palm Beach, Florida, a state-of-the-art stadium with 8,000 seats shared by Astros and Nationals, featuring excellent spring training amenities and recent upgrades for fan comfort.

Astros are predicted to win with moneyline odds of 1.65 on DexWin, leveraging their veteran core like Yordan Alvarez and pitching depth against Marlins' young rotation battles involving Sandy Alcantara and Eury Pérez post-Tommy John recoveries.

In recent head-to-head matchups over the last 10 meetings, Houston Astros hold a 6-4 edge over Miami Marlins, averaging 4.8 total runs per game with Astros scoring 2.9 on average; Marlins won 2 of the last 5 but Astros dominated Spring Training clashes last year.