Arizona Diamondbacks are favored to win with odds around 1.75 due to their stronger projected lineup featuring Ketel Marte and Corbin Carroll, while the Rockies struggle with pitching woes and a 100-loss trend over recent seasons. DexWin - Best Odds on Your Favourite Sports. The Diamondbacks' recent additions like Nolan Arenado give them an edge in this early Spring Training matchup at Salt River Fields.

The match starts at 8:10 PM MST on February 21, 2026, which aligns with 3:10 AM UTC the next day, marking one of the first games in MLB Spring Training.

The game takes place at Salt River Fields at Talking Stick in Scottsdale, Arizona, a state-of-the-art Spring Training facility shared by the Diamondbacks and Rockies with a capacity of 11,000 seats and modern amenities for fans.

Prediction favors the Arizona Diamondbacks to win with moneyline odds of 1.75 on DexWin, bolstered by their offensive depth including Paul Goldschmidt and improved rotation depth despite pitching concerns, contrasting the Rockies' weak projections and recent 119 near-loss record.

In recent head-to-head Spring Training matchups, the Diamondbacks hold a 6-4 edge over the last 10 meetings, with Arizona averaging 5.2 runs per game compared to Colorado's 4.1, highlighting the D-backs' consistent superiority early in the season.