Bet on Los Angeles Rams vs San Francisco 49ers on American Football
Who is favored to win and why?
San Francisco 49ers are favored with odds of 1.80 compared to Los Angeles Rams at 2.10. The 49ers have won 7 of their last 10 matchups and hold a superior defensive record this season.
What is the match start time?
The match starts at 9:25 PM EST on November 9, 2025 at SoFi Stadium in Inglewood, California.
Where is the venue located?
The game will be played at SoFi Stadium, home of the Los Angeles Rams, with a capacity of 70,240 and a retractable roof.
What is the prediction with odds analysis?
San Francisco 49ers are predicted to win with moneyline odds of 1.80. They have a 7-3 record against the Rams in the past five years and average 26.1 points per game in recent matchups.
What is the head-to-head record between the teams?
In their last 10 meetings, San Francisco 49ers have won 7 games to the Rams' 3. The overall head-to-head record stands at 79-71-3 in favor of the 49ers across all competitions.