Bet on Indianapolis Colts vs Kansas City Chiefs on American Football

Kansas City Chiefs are favored to win with moneyline odds around -208, while Indianapolis Colts are listed at +173. The Chiefs have a higher win probability based on recent performance and odds, with consensus picks favoring them to cover the spread.

The match starts at 1:00 PM EST on November 23, 2025, which is 6:00 PM UTC.

The game will be played at Arrowhead Stadium in Kansas City, Missouri, home of the Chiefs, with a seating capacity of approximately 76,416.

Kansas City Chiefs are predicted to win, with consensus picks favoring them to cover the -3.5 spread and the under hitting for the total points. Recent odds and expert picks consistently back the Chiefs to win outright and cover the spread.

In their recent head-to-head matchups, the Kansas City Chiefs have dominated, winning the majority of their last meetings. The Chiefs hold a clear advantage in both regular season and playoff encounters over the past several seasons.