Bet on Cincinnati Bengals vs Buffalo Bills on American Football

Buffalo Bills are favored to win with odds around 1.40, while Cincinnati Bengals are listed at approximately 2.85. The Bills have a stronger recent record, standing at 7-4 SU compared to the Bengals' 4-8 SU, and have shown consistent performance in their last 25 games.

The match starts at 1:00 PM EST on December 7, 2025.

The game will be played at Highmark Stadium in Orchard Park, New York, which is the home venue for the Buffalo Bills.

Buffalo Bills are predicted to win based on their superior record and recent form. The odds reflect their dominance, with the Bills winning 18 of their last 25 games and the total going under in 5 of their last 7 matchups.

The Buffalo Bills have a 4-6 record against the Cincinnati Bengals in their last 10 meetings, indicating a competitive head-to-head history with a slight edge to the Bengals in recent matchups.