Bet on Carolina Panthers vs Tampa Bay Buccaneers on American Football

Tampa Bay Buccaneers are favored to win with -155 moneyline odds and a 3-point spread over the Carolina Panthers, due to their stronger recent form including 8-6 straight-up record and covering in simulations 55% of the time despite recent ATS struggles, while the Panthers sit as +130 underdogs with alternating cover results. Key Buccaneers players like Baker Mayfield and Mike Evans are expected to drive the offense at Bank of America Stadium.

The match starts at 6:00 PM ET on January 4, 2026, which aligns with typical NFL scheduling for high-stakes divisional games like this NFC South clash.

The game is at Bank of America Stadium in Charlotte, North Carolina, home of the Carolina Panthers with a capacity of 74,867 seats, featuring modern amenities and a passionate crowd for this pivotal matchup.

Prediction favors Tampa Bay Buccaneers to win 28-22 with -155 moneyline odds on DexWin - Best Odds on Your Favourite Sports; their model simulation win probability is 63% and they cover the 3-point spread in 55% of scenarios, bolstered by superior offensive output against a Panthers defense that has shown vulnerability in recent home underdog spots.

In recent head-to-heads, Tampa Bay Buccaneers hold the edge with consistent wins including covering seven straight against similar opponents, while Carolina Panthers lead the NFC South temporarily at 8-7 to Tampa's 7-8 but trail in simulations and divisional projections.