Who is favored to win in Carolina Panthers vs San Francisco 49ers?
San Francisco 49ers are favored to win with moneyline odds around -320, while the Carolina Panthers are listed at +260. The 49ers have a stronger recent record and are playing at home, contributing to their favored status.
What time is Carolina Panthers vs San Francisco 49ers?
The match starts at 1:15 AM UTC on November 25, 2025, which is 5:15 PM PST on November 24, 2025, in the local time zone.
Where is Carolina Panthers vs San Francisco 49ers being held?
The game will be played at Levi's Stadium in Santa Clara, California, which has a capacity of approximately 68,500 and is the home venue for the San Francisco 49ers.
Carolina Panthers vs San Francisco 49ers prediction & odds - who wins?
San Francisco 49ers are predicted to win based on their superior recent form and home advantage, with moneyline odds of -320 and a point spread of -7. The total points line is set at 47.5, reflecting expectations of a moderate-scoring game.
What is the head to head record between Carolina Panthers vs San Francisco 49ers?
The San Francisco 49ers hold a strong head-to-head record against the Carolina Panthers, with the 49ers winning 4 of their last 5 meetings. The 49ers are also 4-14 against the spread in their last 18 games against the Panthers, indicating a historical edge but frequent struggles to cover the spread.
