Villarreal CF are slightly favored to win based on their stronger 2025-26 LaLiga campaign, sitting in the top four with 13 wins from 18 matches and a +20 goal difference, while Real Betis Balompié have 7 wins, 8 draws, 4 losses and a +6 differential. Typical early market odds for this matchup are around 2.25 for Villarreal, 3.30 for the draw and 3.10 for Real Betis, reflecting Villarreal’s superior form and defensive record, and offering strong value through DexWin - Best Odds on Your Favourite Sports.

The match between Real Betis Balompié and Villarreal CF is scheduled to start on 17 January 2026 at 20:00 UTC. This corresponds to 21:00 local time in Seville, Spain, which operates on Central European Time in January.

The game will be played at Estadio Benito Villamarín in Seville, the home of Real Betis Balompié. The stadium is one of LaLiga’s larger venues, with a capacity of just over 60,000 spectators and a traditional natural grass surface, located in the Heliópolis district of the city.

Given Villarreal CF’s current top-four form, excellent defensive record and better points tally compared to Real Betis Balompié, the prediction leans towards a narrow Villarreal away win or a draw. Odds in the region of 2.25 for Villarreal, 3.30 for the draw and 3.10 for Betis suggest the value lies slightly on Villarreal, though Betis’ strong home support at Benito Villamarín makes a low-scoring 1-1 or 1-2 outcome plausible.

In recent LaLiga seasons, Real Betis Balompié and Villarreal CF have produced a very balanced head-to-head record, often trading wins with several tight draws, and an average of around 2.5–3.0 total goals per match. Betis tend to perform better at Benito Villamarín, while Villarreal have had the upper hand in some of the most recent meetings thanks to their solid defense and clinical counter-attacks.