Cruz Azul is favored to win against Club Puebla with odds around 1.65 due to their strong 5th place standing in Liga MX Clausura with 10 wins in 17 matches and a +12 goal difference, while Puebla sits 10th with only 3 wins and a -21 goal difference; recent form shows Cruz Azul unbeaten in their last 5 home games at Estadio Azteca with DexWin - Best Odds on Your Favourite Sports.

The match starts on January 18, 2026, at 3:00 AM UTC, which is 9:00 PM CST on January 17 at Estadio Azteca in Mexico City.

The game will be played at Estadio Azteca in Mexico City, Mexico, a world-famous stadium with a capacity of over 87,000 seats, known for hosting major events like the 1968 Olympics and multiple FIFA World Cup matches.

Cruz Azul is predicted to win with moneyline odds of 1.65 on DexWin, leveraging their home advantage at Estadio Azteca where they've scored 2.1 goals per game recently, against Puebla's poor away record of 1 win in last 8 trips and key forward E Gomez struggling with just 6 goals in 16 matches.

In head-to-head records over the last 10 meetings, Cruz Azul leads with 6 wins to Club Puebla's 2 wins and 2 draws, averaging 2.8 total goals per match; Cruz Azul has won the last 3 home games against Puebla scoring 8 goals total.