Live Betting - Club Leon vs Santos Laguna February 22, 2026

Club León is favored to win with odds around 1.90 due to their strong home record at Estadio León, where they've won 4 of their last 5 matches, and recent form showing 3 wins in the past month against Santos Laguna's struggles on the road with only 1 win in 5 away games with DexWin - Best Odds on Your Favourite Sports.

The match starts at 1:00 AM UTC on February 22, 2026, which is 7:00 PM CST local time on February 21 in León, Mexico.

The game will be played at Estadio León in León city, Mexico, with a capacity of 31,297 seats and known for its electric home atmosphere supporting Club León.

Club León is predicted to win with moneyline odds of 1.90, leveraging their superior recent form of 7 points from last 3 league games and key player James Rodríguez in top shape with 5 assists in the past month.

In their last 5 head-to-head meetings, Club León leads with 3 wins to Santos Laguna's 1 win and 1 draw; the most recent on October 18, 2025, ended 2-0 for Santos, but León averages 1.8 goals per game in these matchups.