Live Betting - St. Louis Cardinals vs Houston Astros February 22, 2026

The Houston Astros are favored in this spring training matchup with their stronger projected roster and recent offseason acquisitions, though spring training games carry less predictive weight than regular season contests. The Astros are projected for a .528 winning percentage in 2026 according to PECOTA projections, while the Cardinals are focused on development and integration of young prospects like JJ Wetherholt.

The match starts at 2:05 PM local time on February 22, 2026. The exact timezone depends on the spring training facility location, which is typically in Arizona (MST) or Florida (EST) during spring training season.

Spring training games in 2026 are held at various facilities across Arizona and Florida. The specific venue for this Cardinals-Astros matchup would be either the Astros' spring training home in West Palm Beach, Florida or the Cardinals' facility in Jupiter, Florida, though the exact stadium details require confirmation of the spring training schedule.

Houston enters 2026 with significant roster questions after missing the playoffs for the first time since 2020, but the Astros have 11 players projected to post a 99 wRC+ or better with Yordan Alvarez leading the way. St. Louis is in a rebuilding phase with prospects like JJ Wetherholt expected to make their MLB debut, making this a matchup between a team seeking to return to contention and one focused on youth development.

Head-to-head records between the Cardinals and Astros in spring training are not provided in available projections, as spring training matchups vary annually and carry minimal historical significance compared to regular season records. Both teams will use these games to evaluate roster depth and prospect readiness ahead of the 2026 regular season.